Collagen

A Multi-Center, Double-Blind, Randomized, Comparator Controlled Trial Evaluating Topical Formulations for Skin Fragility of the Arms (2024)

Clinical and histologic findings after use of a novel combined retinol, tripeptide, and glaucine containing cream in the treatment of photo-aged skin (2023)

Efficacy and mechanism of retinyl palmitate against UVB-induced skin photoaging (2023)

Restoration of Aging Body Skin: Evidence-Based Development of a Topical Formulation for Improving Body Skin Quality (2023)

Hesperidin, Hesperetin, Rutinose, and Rhamnose Act as Skin Anti-Aging Agents (2023)

Impact of defensins-containing body cream on skin composition (2023)

Cosmetic Formulations with Melaleuca alternifolia Essential Oil for the Improvement of Photoaged Skin: A Double-Blind, Randomized, Placebo-Controlled Clinical Study (2023)

Biomarkers of Tretinoin Precursors and Tretinoin Efficacy in Patients With Moderate to Severe Facial Photodamage: A Randomized Clinical Trial (2022)

Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide (2022)

Effect of a Topical Collagen Tripeptide on Antiaging and Inhibition of Glycation of the Skin: A Pilot Study (2022)

Rationale and Preclinical Evaluation of a Multimodal Topical Body Skincare Product for Toning and Tightening (2021)

Prospective, Randomized, Comparative Study of the Cutaneous Effects of a Topical Body Treatment Compared to a Bland Moisturizer (2021)

Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study (2021)

Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study (2021)

Efficacy and Tolerability of a Novel Topical Treatment for Neck: A Randomized, Double-blind, Regimen-Controlled Study (2021)

Clinical Benefits of Circadian-based Antioxidant Protection and Repair (2020)

Night Cream Containing Melatonin, Carnosine and Helichrysum italicum Extract Helps Reduce Skin Reactivity and Signs of Photodamage: Ex Vivo and Clinical Studies (2020)

A novel skin brightening topical technology (2020)

Efficacy and safety of a 3-in-1 antiaging night facial serum containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate through clinical and histological analysis (2020)

Epidermal and Dermal Hallmarks of Photoaging are Prevented by Treatment with Night Serum Containing Melatonin, Bakuchiol, and Ascorbyl Tetraisopalmitate: In Vitro and Ex Vivo Studies (2020)

Novel Hydrolyzed Chicken Sternal Cartilage Extract Improves Facial Epidermis and Connective Tissue in Healthy Adult Females: A Randomized, Double-Blind, Placebo-Controlled Trial (2019)

Potentially beneficial effects of rhamnose on skin ageing: an in vitro and in vivo study (2019)

A single-center clinical trial to evaluate the efficacy of a tripeptide/hexapeptide antiaging regimen (2019)

Comparable efficacy of adapalene 0.3% gel and tretinoin 0.05% cream as treatment for cutaneous photoaging (2018)

Collagen concentration on the facial skin of postmenopausal women after topical treatment with estradiol and genistein: a randomized double-blind controlled trial (2017)

Climbazole boosts activity of retinoids in skin (2017)

An Insight into the Changes in Skin Texture and Properties following Dietary Intervention with a Nutricosmeceutical Containing a Blend of Collagen Bioactive Peptides and Antioxidants (2017)

Biological effects of rutin on skin aging (2016)

Ability of sodium copper chlorophyllin complex to repair photoaged skin by stimulation of biomarkers in human extracellular matrix (2016)

The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials (2015)

Randomized, double-blinded, vehicle-controlled, split-face study to evaluate the effects of topical application of a Gold Silk Sericin/Niacinamide/Signaline complex on biophysical parameters related to skin ageing (2015)

Total Defense + Repair: A Novel Concept in Solar Protection and Skin Rejuvenation (2015)

4-Hexyl-1,3-phenylenediol, a nuclear factor-κB inhibitor, improves photodamaged skin and clinical signs of ageing in a double-blinded, randomized controlled trial (2015)

Assessment of clinical effects and safety of an oral supplement based on marine protein, vitamin C, grape seed extract, zinc, and tomato extract in the improvement of visible signs of skin aging in men (2015)

In vitro and in vivo studies with tetra-hydro-jasmonic acid (LR2412) reveal its potential to correct signs of skin ageing (2014)

Long-term topical oestrogen treatment of sun-exposed facial skin in post-menopausal women does not improve facial wrinkles or skin elasticity, but induces matrix metalloproteinase-1 expression (2014)

Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis (2013)

A double-blind controlled clinical trial assessing the effect of topical gels on striae distensae (stretch marks): a non-invasive imaging, morphological and immunohistochemical study (2013)

The anti-wrinkle efficacy of Argireline (2013)

Hypo-collagenesis in photoaged skin predicts response to anti-aging cosmeceuticals (2013)

Efficacy of a novel treatment serum in the improvement of photodamaged skin (2013)

Photo-damage protective effect of two facial products, containing a unique complex of Dead Sea minerals and Himalayan actives (2012)

Ingestion of BioCell Collagen(®), a novel hydrolyzed chicken sternal cartilage extract; enhanced blood microcirculation and reduced facial aging signs (2012)

Pycnogenol® effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women (2012)

Dermal penetration of creatine from a face-care formulation containing creatine, guarana and glycerol is linked to effective antiwrinkle and antisagging efficacy in male subjects (2011)

Salicin regulates the expression of functional 'youth gene clusters' to reflect a more youthful gene expression profile (2011)

Retinyl retinoate, a novel hybrid vitamin derivative, improves photoaged skin: a double-blind, randomized-controlled trial (2011)

Folic acid and creatine improve the firmness of human skin in vivo (2011)

Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin (2010)

Clinical Safety and Efficacy in Photoaged Skin With CoffeeBerry Extract, a Natural Antioxidant (2009)

In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation (2009)

Effects of a cosmetic 'anti-ageing' product on photoaged skin (2009)

A two-year, double-blind, randomized placebo-controlled trial of oral green tea polyphenols on the long-term clinical and histologic appearance of photoaging skin (2009)

Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin (2008)

Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivo (2008)

Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative (2008)

Clinical, histologic, and ultrastructural changes after use of human growth factor and cytokine skin cream for the treatment of skin rejuvenation (2008)

Improvement of naturally aged skin with vitamin A (retinol) (2007)

Efficacy and tolerability of kinetin 0.1% cream for improving the signs of photoaging in facial and neck skin (2006)

Pharmacological properties of rhamnose-rich polysaccharides, potential interest in age-dependent alterations of connectives tissues (2006)

Clinical efficacy assessment in photodamaged skin of 0.5% and 1.0% idebenone (2005)

Novel aspects of intrinsic and extrinsic aging of human skin: beneficial effects of soy extract (2005)

Long-term efficacy and safety of tretinoin emollient cream 0.05% in the treatment of photodamaged facial skin: a two-year, randomized, placebo-controlled trial (2005)

Effect of L-fucose and fucose-rich polysaccharides on elastin biosynthesis, in vivo and in vitro (2004)

Effects of L-fucose and fucose-rich oligo- and polysaccharides (FROP-s) on collagen biosynthesis by human skin fibroblasts. Modulation of the effect of retinol, ascorbate and alpha-tocopherol (2004)

Effect of L-fucose and fucose-rich oligo- and polysaccharides (FROP-s) on skin aging: penetration, skin tissue production and fibrillogenesis (2003)

Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo (2003)

The effects of an estrogen and glycolic acid cream on the facial skin of postmenopausal women: a randomized histologic study (2003)

Reversal of photodamage with topical growth factors: a pilot study (2003)

High global antioxidant protection and stimulation of the collagen synthesis of new anti-aging product containing an optimized active mix (2002)

Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage (2002)

Tazarotene cream for the treatment of facial photodamage: a multicenter, investigator-masked, randomized, vehicle-controlled, parallel comparison of 0.01%, 0.025%, 0.05%, and 0.1% tazarotene creams with 0.05% tretinoin emollient cream applied once daily for 24 weeks (2001)

Repair of UVA-induced elastic fiber and collagen damage by 0.05% retinaldehyde cream in an ex vivo human skin model (1999)

A clinicopathological study of the effects of topical retinyl propionate cream in skin photoageing (1998)

Treatment of skin aging with topical estrogens (1996)

Topical tretinoin (retinoic acid) improves early stretch marks (1996)

Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study (1996)

The effect of topical oestradiol on skin collagen of postmenopausal women (1995)

Regulation of collagen synthesis in human dermal fibroblasts by the sodium and magnesium salts of ascorbyl-2-phosphate (1993)

Topical tretinoin (retinoic acid) treatment for liver spots associated with photodamage (1992)

Effects of tretinoin on photodamaged skin. A histologic study (1991)

Sustained improvement with prolonged topical tretinoin (retinoic acid) for photoaged skin (1990)

Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts (1987)