Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study

Study Design

Subject Type

Human

Trial Design

Single-Blind, Randomised, Controlled

Trial Duration

168 days

Participants

17 (17 completed)

Age Range

52-83 years

Efficacy

Intervention(s)			Outcome		Method		Effect	Description
Lactic Acid			Skin Thickness		Micrometer calipers		🠩	Sign in to read for free
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Glycolic Acid			Skin Thickness		Micrometer calipers		🠩	Sign in to read for free
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Citric Acid			Skin Thickness		Micrometer calipers		🠩	Sign in to read for free
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Mechanisms

Intervention(s)			Outcome		Method		Effect	Description
Lactic Acid			Collagen		Histology		–	Sign in to read for free
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Citric Acid			Collagen		Histology		–	Sign in to read for free
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Glycolic Acid			Collagen		Histology		–	Sign in to read for free
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Lactic Acid			Elastic Fibres		Histology		–	Sign in to read for free
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Glycolic Acid			Elastic Fibres		Histology		–	Sign in to read for free
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Citric Acid			Elastic Fibres		Histology		–	Sign in to read for free
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Lactic Acid			Glycosaminoglycans		Histology		⇧	Sign in to read for free
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Citric Acid			Glycosaminoglycans		Histology		⇧	Sign in to read for free
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Glycolic Acid			Glycosaminoglycans		Histology		⇧	Sign in to read for free
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Lactic Acid			Inflammation		Histology		–	Sign in to read for free
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Glycolic Acid			Inflammation		Histology		–	Sign in to read for free
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Citric Acid			Inflammation		Histology		–	Sign in to read for free
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Study Summary

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