Tetrahydrojasmonic acid is a synthetic derivative of jasmonic acid, a plant hormone that plays a role in plant stress regulation, wound repair and defence (R).
Tetrahydrojasmonic acid is amphiphilic and can permeate human skin. Within 24 hours after application, 0.9% of the dose was detected in the stratum corneum, 0.7% in the epidermis, 0.3% in the dermis and 3.6% had penetrated through the dermis (R).
| Outcome | Grade | Effect | Studies | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Fibrillin | 
        C
       | 
 | 
 | |||||||
| Hyaluronan Synthase | 
        D
       | 
 | ||||||||
| Collagen | 
        D
       | 
 | ||||||||
| Keratinocyte Proliferation | 
        D
       | 
 | ||||||||
| Laminin | 
        D
       | 
 | ||||||||