Safety and efficacy of combined essential oils for the skin barrier properties: In vitro, ex vivo and clinical studies

Study Design

Subject Type

Human

Trial Design

Double-Blind, Randomised, Controlled

Trial Duration

90 days

Participants

40 (37 completed)

Age Range

18-28 years

Efficacy

Intervention(s)	Outcome	Method	Effect	Description
Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil + Tea Tree Oil	Skin Barrier Function	Tewameter	🠩	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil	Skin Barrier Function	Tewameter	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil + Tea Tree Oil	Skin Hydration	Corneometer	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil	Skin Hydration	Corneometer	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil + Tea Tree Oil	Skin Oiliness	Sebumeter	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil	Skin Oiliness	Sebumeter	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil + Tea Tree Oil	Skin Thickness	Reflectance confocal microscopy	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil	Skin Thickness	Reflectance confocal microscopy	–	Sign in to read for free
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Mechanisms

Intervention(s)	Outcome	Method	Effect	Description
Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil	Cell Viability	Assay	⇩	Sign in to read for free
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Tea Tree Oil	Cell Viability	Assay	–	Sign in to read for free
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Eucalyptus Leaf Oil	Cell Viability	Assay	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil + Tea Tree Oil	Cell Viability	Assay	⇩	Sign in to read for free
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Tangerine Peel Oil	Cell Viability	Assay	⇩	Sign in to read for free
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Lavender Oil	Cell Viability	Assay	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil	Dermal Papillae	Reflectance confocal microscopy	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil + Tea Tree Oil	Dermal Papillae	Reflectance confocal microscopy	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil + Tea Tree Oil	Stratum Corneum Compaction	Reflectance confocal microscopy	–	Sign in to read for free
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Eucalyptus Leaf Oil + Lavender Oil + Tangerine Peel Oil	Stratum Corneum Compaction	Reflectance confocal microscopy	–	Sign in to read for free
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Study Summary