A histological examination for skin atrophy after 6 months of treatment with fluocinolone acetonide 0.01%, hydroquinone 4%, and tretinoin 0.05% cream

Study Design
Subject Type
Human
Trial Design
N.A.
Trial Duration
168 days
Participants
70 (62 completed)
Age Range
18-65 years
Efficacy
Intervention(s) Outcome
Melasma
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Mechanisms
Intervention(s) Outcome
Blood Vessels
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Elastic Fibres
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Glycosaminoglycans
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Melanin
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Stratum Corneum Compaction
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Side Effects
Intervention(s) Outcome
Cell Viability
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Inflammation
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Keratinocyte Atypia
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Melanocyte Atypia
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Skin Thickness
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Spider Veins
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Study Summary
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