Hyaluronic Acid + Thiamidol

Efficacy

Mechanisms

Outcome				Grade		Effect		Evidence		Studies
Melanin				E		– No Effect		★★ Some		1 study 60 participants

Side Effects

Outcome			Effect		Frequency			Studies
Itching			⇧ Increase		7% (2 out of 30 participants)			1 study
Skin Discomfort			⇧ Increase		7% (2 out of 30 participants)			1 study

Latest Research

Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial (2021)