| Outcome | Grade | Effect | Studies | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Hyperpigmentation | 
        C
       | 
 | 
 | |||||||
| Skin Brightness | 
        C
       | 
 | 
 | |||||||
| Spider Veins | 
        C
       | 
 | 
 | |||||||
| Skin Redness | 
        C
       | 
 | 
 | |||||||
| Melasma | 
        C
       | 
 | 
 | |||||||
| Outcome | Effect | Frequency | Studies | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Itching | ⇧ Increase | 
 | ||||||||
| Peeling | ⇧ Increase | 
 | ||||||||
| Skin Discomfort | ⇧ Increase | 
 | ||||||||
| Acne | ⇧ Increase | 
 | ||||||||
| Skin Hydration | ⇩ Decrease | 
 | ||||||||